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JUND
Loading...Anti-JUND Products
- AbPlus™ Anti-JUND Magnetic Beads (CBACN-335) (VS-0424-XY165)
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- Target: JUND
- Target Species: Human
- Application: IP, Protein Purification
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- Anti-JUND Immunohistochemistry Kit (VS-0325-XY1169)
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- Species Reactivity: Human
- Target: JUND
- Application: IHC
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- Anti-Human JUND Immunohistochemistry Kit (VS-0525-XY3706)
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- Species Reactivity: Human
- Target: JUND
- Application: IHC
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More Infomation
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For Research Use Only. Not For Clinical Use.
Background
JUND is a member of the JUN family, and a functional component of the AP1 transcription factor complex. This protein has been proposed to protect cells from p53-dependent senescence and apoptosis.
Protein class
Cancer-related genes, Plasma proteins, Transcription factors
Predicted location
Intracellular
Single cell type specificity
Cell type enhanced (Adipocytes, dendritic cells)
Immune cell specificity
Low immune cell specificity
Cell line specificity
Low cell line specificity
Interaction
Heterodimer; binds DNA as a heterodimer (PubMed:28981703). Component of an AP-1 transcription factor complex composed of JUN-FOS heterodimers (By similarity). As part of the AP-1 transcription factor complex, forms heterodimers with FOS proteins, thereby binding to the AP-1 consensus sequence and stimulating transcription (By similarity). Forms heterodimers with FOSB; thereby binding to the AP-1 consensus sequence (PubMed:28981703). Interacts (via MBM motif) with MEN1; this interaction represses transcriptional activation (PubMed:9989505, 22327296). Interacts with MAPK10; this interaction is inhibited in the presence of MEN1 (PubMed:22327296).
Molecular function
Activator, DNA-binding
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