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For Research Use Only. Not For Clinical Use.
Disease related genes, FDA approved drug targets, Human disease related genes, Transporters, Voltage-gated ion channels
Membrane
Cell type enhanced (Excitatory neurons, Inhibitory neurons, Bipolar cells, Oligodendrocyte precursor cells, Cardiomyocytes, Hepatocytes)
Not detected in immune cells
Cell line enhanced (OE19, SCLC-21H, U-2 OS, WM-115)
Homotetramer or heterotetramer with KCND1 and/or KCND2. Associates with the regulatory subunits KCNIP1, KCNIP2, KCNIP3 and KCNIP4 (By similarity). Interacts with KCNE1, KCNE2, SCN1B and KCNAB1 and DLG1.
Ion channel, Potassium channel, Voltage-gated channel