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KCNJ10
Anti-KCNJ10 Recombinant Antibody Products
- Recombinant Anti-human KCNJ10 Antibody (MOB-597)
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- Derivation: Mouse
- Species Reactivity: Human
- Type: IgG
- Application: ELISA, WB, Dot, FuncS
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- Recombinant Human Anti-human KCNJ10 Antibody Fab Fragment (MHH-597-F(E))
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- Derivation: Human
- Species Reactivity: Human
- Type: Fab
- Application: FC, WB, FuncS
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- Recombinant Human Anti-human KCNJ10 Antibody scFv Fragment (MHH-597-S(P))
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- Derivation: Human
- Species Reactivity: Human
- Type: scFv
- Application: FC, IP, FuncS
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- Recombinant Anti-human KCNJ10 Antibody Fab Fragment (MOB-597-F(E))
-
- Derivation: Mouse
- Species Reactivity: Human
- Type: Fab
- Application: IF, Neut, FuncS
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- Recombinant Anti-human KCNJ10 Antibody scFv Fragment (MOB-597-S(P))
-
- Derivation: Mouse
- Species Reactivity: Human
- Type: scFv
- Application: Neut, IF, FuncS
Compare
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For Research Use Only. Not For Clinical Use.
This gene encodes a member of the inward rectifier-type potassium channel family, characterized by having a greater tendency to allow potassium to flow into, rather than out of, a cell. The encoded protein may form a heterodimer with another potassium channel protein and may be responsible for the potassium buffering action of glial cells in the brain. Mutations in this gene have been associated with seizure susceptibility of common idiopathic generalized epilepsy syndromes. [provided by RefSeq, Jul 2008]
Protein class
Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Transporters, Voltage-gated ion channels
Predicted location
Intracellular, Membrane (different isoforms)
Single cell type specificity
Group enriched (Oligodendrocytes, Astrocytes, Muller glia cells, Oligodendrocyte precursor cells)
Immune cell specificity
Not detected in immune cells
Cell line specificity
Cell line enhanced (Hep G2, SK-MEL-30, U-266/70)
Interaction
Heterodimer with Kir5. 1/KCNJ16; this interaction is required for KCNJ16 localization to the basolateral membrane in kidney cells. Interacts with MAGI1, alone and possibly as a heterodimer with KCNJ16; this interaction may facilitate KCNJ10/KCNJ16 potassium channel expression at the basolateral membrane in kidney cells (PubMed:24561201). Interacts with PATJ (By similarity).
Molecular function
Ion channel, Voltage-gated channel
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