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KIF1B

his gene encodes a motor protein that transports mitochondria and synaptic vesicle precursors. Mutations in this gene cause Charcot-Marie-Tooth disease, type 2A1.
Protein class

Disease related genes, Human disease related genes, Plasma proteins

Predicted location

Intracellular

Single cell type specificity

Cell type enhanced (Cone photoreceptor cells, Oligodendrocytes, Astrocytes, Rod photoreceptor cells, Excitatory neurons, Inhibitory neurons)

Immune cell specificity

Immune cell enhanced (eosinophil)

Cell line specificity

Low cell line specificity

Interaction

Monomer (By similarity). Interacts (via C-terminus end of the kinesin-motor domain) with CHP1; the interaction occurs in a calcium-dependent manner (By similarity). Interacts with KIFBP (PubMed:16225668). Interacts with MADD (via death domain) (By similarity).

Molecular function

Motor protein

More Types Infomation

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