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KRT83
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For Research Use Only. Not For Clinical Use.
The protein encoded by this gene is a member of the keratin gene family. As a type II hair keratin, it is a basic protein which heterodimerizes with type I keratins to form hair and nails. The type II hair keratins are clustered in a region of chromosome 12q13 and are grouped into two distinct subfamilies based on structure similarity. One subfamily, consisting of KRTHB1, KRTHB3, and KRTHB6, is highly related. The other less-related subfamily includes KRTHB2, KRTHB4, and KRTHB5. All hair keratins are expressed in the hair follicle; this hair keratin, as well as KRTHB1 and KRTHB6, is found primarily in the hair cortex.
Protein class
Disease related genes, Human disease related genes
Predicted location
Intracellular
Single cell type specificity
Not detected
Immune cell specificity
Not detected in immune cells
Cell line specificity
Cell line enriched (RPMI-8226)
Interaction
Heterotetramer of two type I and two type II keratins.
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