LBX1
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- Species Reactivity: Human
- Application: WB
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For Research Use Only. Not For Clinical Use.
Background
This gene and the orthologous mouse gene were found by their homology to the Drosophila lady bird early and late homeobox genes. In the mouse, this gene is a key regulator of muscle precursor cell migration and is required for the acquisition of dorsal identities of forelimb muscles. [provided by RefSeq, Jul 2008]
Protein class
Transcription factors
Predicted location
Intracellular
Single cell type specificity
Cell type enriched (Skeletal myocytes)
Immune cell specificity
Not detected in immune cells
Cell line specificity
Group enriched (HEK93, RH-30, SCLC-21H)
Interaction
Interacts with SKOR1 which acts as a transcriptional corepressor.
Molecular function
Developmental protein, DNA-binding
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