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LIG4

Anti-LIG4 Products

Mouse Anti-LIG4 Recombinant Antibody (clone 6G11) (MOB-1285z)
- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG2a
- Application: WB, ELISA
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Recombinant Rabbit Anti-LIG4 Monoclonal Antibody (JM64-32) (MRO-0481-CN)
- Species Reactivity: Human
- Type: Rabbit IgG
- Application: WB, IHC, IF
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Rabbit Anti-LIG4 Recombinant Antibody (clone JM64-32) (VS3-WK603)
- Derivation: Rabbit
- Species Reactivity: Human
- Type: Rabbit IgG
- Application: WB, ELISA
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Recombinant Rabbit Anti-LIG4 Antibody (clone R08-3B4) (VS3-FY848)
- Species Reactivity: Human
- Type: Rabbit IgG
- Application: WB
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For Research Use Only. Not For Clinical Use.

Background

The protein encoded by this gene is an ATP-dependent DNA ligase that joins double-strand breaks during the non-homologous end joining pathway of double-strand break repair. It is also essential for V(D)J recombination. Lig4 forms a complex with XRCC4, and further interacts with the DNA-dependent protein kinase (DNA-PK) and XLF/Cernunnos, which are also required for NHEJ.