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LMO4

Anti-LMO4 Recombinant Antibody Products

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For Research Use Only. Not For Clinical Use.


Enables DNA-binding transcription factor binding activity and transcription corepressor activity. Involved in several processes, including negative regulation of transcription by RNA polymerase II; nervous system development; and positive regulation of kinase activity. Acts upstream of or within several processes, including cell differentiation in spinal cord; thymus development; and ventricular septum development. Located in cell leading edge and nucleus. Part of RNA polymerase II transcription regulator complex. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; integumental system; and sensory organ.
Predicted location

Intracellular

Single cell type specificity

Cell type enhanced (Endometrial stromal cells)

Immune cell specificity

Low immune cell specificity

Cell line specificity

Cell line enhanced (AN3-CA, T-47d)

Interaction

Interacts strongly with LDBS. Interacts with DEAF1; LMO4 blocks export from nucleus. Interacts with CLIM1 and CLIM2. Interacts (via the LIM zinc-binding domain 1) with RBBP8. Interacts with BRCA1 (via the BRCT domains); the interaction represses BRCA1 transcriptional activity (By similarity).

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