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LMOD1
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For Research Use Only. Not For Clinical Use.
Background
The leiomodin 1 protein has a putative membrane-spanning region and 2 types of tandemly repeated blocks. The transcript is expressed in all tissues tested, with the highest levels in thyroid, eye muscle, skeletal muscle, and ovary. Increased expression of leiomodin 1 may be linked to Graves' disease and thyroid-associated ophthalmopathy.
Protein class
Plasma proteins
Predicted location
Intracellular
Single cell type specificity
Cell type enhanced (Peritubular cells, Smooth muscle cells, Sertoli cells, Cone photoreceptor cells, Leydig cells, Rod photoreceptor cells)
Immune cell specificity
Not detected in immune cells
Cell line specificity
Cell line enhanced (ASC diff, BJ, BJ hTERT+, fHDF/TERT166, HSkMC, hTERT-RPE1)
Molecular function
Actin-binding
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