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LMP1

Anti-LMP1 Products
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- Species Reactivity: Multiple
- Type: scFv
- Recombinant Anti-TES1 Intrabody [(D-Arg)9] (IAB-B065(A))
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- Type: scFv-(D-Arg)9
- Application: ICC, Neut, FuncS
- Recombinant Anti-TES1 Intrabody [+36 GFP] (IAB-B065(G))
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- Type: scFv-(+36GFP)
- Application: ELISA, WB, ICC, FuncS
- Recombinant Anti-TES1 Intrabody [Tat] (IAB-B065(T))
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- Type: scFv-Tat
- Application: WB, ICC, FuncS
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For Research Use Only. Not For Clinical Use.
Background
The Epstein-Barr virus (EBV) latent membrane protein 1 (LMP1) can express constitutively in many EBVassociated tumors, including Hodgkin's disease, B cell lymphoproliferative disease, and a portion of T cell lymphomas and nasopharyngeal carcinoma (NPC). LMP1 expression has profound effects on target cells, including B lymphocyte and rodent fibroblast transformation, cell apoptosis inhibition by anti-apoptotic protein upregulation, cell surface marker and DNA methyltransferase activity upregulation, and cell adhesion molecule and cyclin-dependent kinase downregulation.