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LRRFIP1

It binds to the GC-rich consensus sequence (5'-AGCCCCCGGCG-3') and may regulate expression of TNF, EGFR and PDGFA. May control smooth muscle cells proliferation following artery injury through PDGFA repression. May also bind double-stranded RNA., sequence caution:Contaminating sequence. Potential poly-A sequence., similarity:Belongs to the LRRFIP family., subunit:Interacts with FLII., tissue specificity:Ubiquitously expressed.,
Protein class

Plasma proteins, Transcription factors

Predicted location

Intracellular

Single cell type specificity

Low cell type specificity

Immune cell specificity

Low immune cell specificity

Cell line specificity

Cell line enhanced (HDLM-2)

Interaction

Homodimer. May also form higher oligomers. Interacts with FLII. Interacts with MYD88. Competes with FLII for MyD88-binding, even in the absence of LPS.

Molecular function

DNA-binding, Repressor

More Types Infomation

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For Research Use Only. Not For Clinical Use.

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