LSM1
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Loading...- AbPlus™ Anti-LSM1 Magnetic Beads (VS-0724-YC475) (VS-0724-YC475)
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- Target: LSM1
- Target Species: Human
- Application: IP, Protein Purification
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- Anti-LSM1 Immunohistochemistry Kit (VS-0525-XY4112)
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- Species Reactivity: Human
- Target: LSM1
- Application: IHC
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- Anti-Mouse LSM1 Immunohistochemistry Kit (VS-0525-XY4113)
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- Species Reactivity: Human, Mouse, Rat, Canine
- Target: LSM1
- Application: IHC
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- Chicken Anti-LSM1 Polyclonal IgY (BRD-0329MZ)
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- Species Reactivity: Human, Mouse, Rat
- Type: Chicken antibody
- Application: WB
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For Research Use Only. Not For Clinical Use.
Background
This gene encodes a member of the LSm family of RNA-binding proteins. LSm proteins form stable heteromers that bind specifically to the 3'-terminal oligo(U) tract of U6 snRNA and may play a role in pre-mRNA splicing by mediating U4/U6 snRNP formation. Increased expression of this gene may play a role in cellular transformation and the progression of several malignancies including lung cancer, mesothelioma and breast cancer.
Predicted location
Intracellular
Single cell type specificity
Low cell type specificity
Immune cell specificity
Low immune cell specificity
Cell line specificity
Low cell line specificity
Interaction
Interacts with SLBP; interaction with SLBP occurs when histone mRNA is being rapidly degraded during the S phase (PubMed:18172165). LSm subunits form a heteromer with a donut shape (By similarity).
Molecular function
Ribonucleoprotein, RNA-binding
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