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LST1

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For Research Use Only. Not For Clinical Use.


The protein encoded by this gene is a membrane protein that can inhibit the proliferation of lymphocytes. Expression of this gene is enhanced by lipopolysaccharide, interferon-gamma, and bacteria. Several transcript variants encoding different isoforms have been found for this gene.
Predicted location

Intracellular, Membrane (different isoforms)

Single cell type specificity

Group enriched (Kupffer cells, Langerhans cells, monocytes, Macrophages, Hofbauer cells)

Immune cell specificity

Immune cell enhanced (non-classical monocyte)

Cell line specificity

Cell line enhanced (HEL, HMC-1, MOLT-4, NB-4, THP-1, U-937)

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