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MAP1LC3A
Loading...Anti-MAP1LC3A Products
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- Derivation: Mouse
- Species Reactivity: Human, Rat, Mouse
- Type: Mouse IgG1
- Application: WB, IHC
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- AbPlus™ Anti-MAP1LC3A Magnetic Beads (VS-0724-YC798) (VS-0724-YC798)
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- Target: MAP1LC3A
- Target Species: Human
- Application: IP, Protein Purification
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- Derivation: Mouse
- Species Reactivity: Human, Mouse, Rat
- Type: Mouse IgG
- Application: WB, ICC, IHC
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- Derivation: Rabbit
- Species Reactivity: Human, Mouse, Rat
- Type: Rabbit IgG
- Application: WB, ICC, IHC, IP
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- AbPlus™ Anti-MAP1LC3A Magnetic Beads (CBACN-352) (VS-0424-XY179)
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- Target: MAP1LC3A
- Target Species: Human, Mouse, Rat
- Application: IP, Protein Purification
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- Derivation: Phage display library screening
- Species Reactivity: Human
- Type: IgG
- Application: ICC, IC, IP, FC, IHC-P
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- Mouse Anti-MAP1LC3A Recombinant Antibody (clone 7E9E12) (VS7-0425-WR328)
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- Species Reactivity: Human
- Type: Mouse IgG1
- Application: FC
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- Mouse Anti-MAP1LC3A Recombinant Antibody (clone 5B10D8) (VS7-0425-WR329)
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- Species Reactivity: Human
- Type: Mouse IgG1
- Application: IHC, FC
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- Anti-MAP1LC3A Immunohistochemistry Kit (VS-0525-XY4195)
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- Species Reactivity: Human
- Target: MAP1LC3A
- Application: IHC
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- Anti-Mouse MAP1LC3A Immunohistochemistry Kit (VS-0525-XY4196)
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- Species Reactivity: Human, Mouse
- Target: MAP1LC3A
- Application: IHC
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For Research Use Only. Not For Clinical Use.
Background
MAP1A and MAP1B are microtubule-associated proteins which mediate the physical interactions between microtubules and components of the cytoskeleton. MAP1A and MAP1B each consist of a heavy chain subunit and multiple light chain subunits. The protein encoded by this gene is one of the light chain subunits and can associate with either MAP1A or MAP1B. Two transcript variants encoding different isoforms have been found for this gene. The expression of variant 1 is suppressed in many tumor cell lines, suggesting that may be involved in carcinogenesis. [provided by RefSeq, Feb 2012]
Predicted location
Intracellular
Single cell type specificity
Cell type enhanced (Late spermatids)
Immune cell specificity
Immune cell enriched (neutrophil)
Cell line specificity
Cell line enhanced (HHSteC, HSkMC, SK-BR-3)
Interaction
3 different light chains, LC1, LC2 and LC3, can associate with MAP1A and MAP1B proteins (By similarity). Interacts with TP53INP1 and TP53INP2 (PubMed:19056683, PubMed:22470510). Directly interacts with SQSTM1; this interaction leads to MAP1LC3A recruitment to inclusion bodies containing polyubiquitinated protein aggregates and to inclusion body degradation by autophagy (PubMed:17580304). Interacts with ATG13 (PubMed:24290141, PubMed:23043107). Interacts with ULK1 (PubMed:23043107). Interacts with TBC1D5 (PubMed:22354992). Found in a complex with UBQLN1 and UBQLN2 (PubMed:20529957). Interacts with UBQLN4 (via STI1 1 and 2 domains). Interacts with UBQLN1 in the presence of UBQLN4 (PubMed:23459205). Interacts with TRIM5 (PubMed:25127057). Interacts with MEFV (PubMed:26347139). Interacts with RETREG1, RETREG2 and RETREG3 (PubMed:26040720). Interacts with PICALM. Interacts with the reticulophagy receptor TEX264 (PubMed:31006538, PubMed:31006537). Interacts with MOAP1 (via LIR motif) (PubMed:33783314).
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