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MAP3K13
The protein encoded by this gene is a member of serine/threonine protein kinase family. This kinase contains a dual leucine-zipper motif, and has been shown to form dimers/oligomers through its leucine-zipper motif. This kinase can phosphorylate and activate MAPK8/JNK, MAP2K7/MKK7, which suggests a role in the JNK signaling pathway.
Protein class
Cancer-related genes, Enzymes, Metabolic proteins
Predicted location
Intracellular
Single cell type specificity
Low cell type specificity
Immune cell specificity
Low immune cell specificity
Cell line specificity
Low cell line specificity
Interaction
Homodimer; forms dimers through the leucine-zipper motif. Interacts with the C-terminus of MAPK8IP1 through the kinase catalytic domain. Binds PRDX3. Associates with the IKK complex through the kinase domain.
Molecular function
Kinase, Serine/threonine-protein kinase, Transferase
More Types Infomation
- Recombinant Mouse Anti-MAP3K13 Antibody (MOB-111CQ)
-
- Species Reactivity: Human
- Type: Mouse IgG2a, κ
- Application: ELISA, IF, WB
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For Research Use Only. Not For Clinical Use.