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MAPRE2
Loading...Anti-MAPRE2 Products
- Recombinant Mouse Anti-Human MAPRE2 Antibody (MOB-1776MZ)
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- Species Reactivity: Human
- Type: Mouse antibody
- Application: IHC-P, WB
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- Mouse Anti-NHP MAPRE2 Recombinant Antibody (clone OTI1A3) (VS-1024-XY314)
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- Species Reactivity: Dog, Human, Non-human primate, Rat
- Type: Mouse IgG2b
- Application: WB, IF, FC
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- Anti-MAPRE2 Immunohistochemistry Kit (VS-0325-XY1304)
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- Species Reactivity: Human
- Target: MAPRE2
- Application: IHC
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For Research Use Only. Not For Clinical Use.
Background
The protein encoded by this gene shares significant homology to the adenomatous polyposis coli (APC) protein-binding EB1 gene family. This protein is a microtubule-associated protein that is necessary for spindle symmetry during mitosis. It is thought to play a role in the tumorigenesis of colorectal cancers and the proliferative control of normal cells. Alternative splicing of this gene results in multiple transcript variants.
Protein class
Disease related genes, Human disease related genes, Plasma proteins
Predicted location
Intracellular
Single cell type specificity
Cell type enhanced (Oligodendrocytes, Excitatory neurons)
Immune cell specificity
Low immune cell specificity
Cell line specificity
Cell line enhanced (HUVEC TERT2)
Interaction
Interacts with DCTN1 (PubMed:14514668). Interacts with APC (via C-terminal) (PubMed:9233623, PubMed:14514668). Interacts with monomeric and polymerized tubulin (PubMed:10188731, PubMed:14514668, PubMed:26637975). Interacts with SLAIN1 (PubMed:21646404).
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