+ Filter
Loading...
MRAS
Anti-MRAS Recombinant Antibody Products
CompareMore Infomation
Can't find the products you're looking for? Try to filter in the left sidebar.Filter By Tag
More Infomation
Our customer service representatives are available 24 hours a day, from Monday to Sunday. Contact Us
For Research Use Only. Not For Clinical Use.
This gene encodes a member of the Ras family of small GTPases. These membrane-associated proteins function as signal transducers in multiple processes including cell growth and differentiation, and dysregulation of Ras signaling has been associated with many types of cancer. The encoded protein may play a role in the tumor necrosis factor-alpha and MAP kinase signaling pathways. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Nov 2011]
Protein class
Disease related genes, Enzymes, Human disease related genes, Potential drug targets, RAS pathway related proteins
Predicted location
Intracellular
Single cell type specificity
Cell type enhanced (Cardiomyocytes, Theca cells, Distal tubular cells)
Immune cell specificity
Immune cell enriched (non-classical monocyte)
Cell line specificity
Cell line enhanced (BJ, EFO-21, fHDF/TERT166)
Interaction
Interacts with RGL3. Interacts (active GTP-bound form preferentially) with RGS14 (By similarity). Forms a multiprotein complex with SHOC2, Raf (RAF1) and protein phosphatase 1 (PPP1CA, PPP1CB and PPP1CC).
Molecular function
Hydrolase
More Types Infomation