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MS4A4A

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For Research Use Only. Not For Clinical Use.


Background

This gene encodes a member of the membrane-spanning 4A gene family. Members of this nascent protein family are characterized by common structural features, similar intron/exon splice boundaries, and display unique expression patterns in hematopoietic cells and nonlymphoid tissues. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2011]
Predicted location

Membrane

Single cell type specificity

Group enriched (Kupffer cells, Hofbauer cells, Macrophages)

Immune cell specificity

Group enriched (non-classical monocyte, intermediate monocyte, plasmacytoid DC, myeloid DC)

Cell line specificity

Cell line enhanced (HEL, HMC-1, K-562)

Molecular function

Receptor

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