Anti-MSMB Products

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For Research Use Only. Not For Clinical Use.

Explore the biology and cancer progression of the prostate gland with Creative Biolabs' specific anti-MSMB (PSP94) recombinant antibodies. MSMB, one of the most abundant proteins secreted by the prostate gland, is emerging as a potential tumor suppressor in prostate cancer. Creative Biolabs' antibodies are ready-to-use, high-quality tools to help you study the role of this mysterious protein in prostate biology and cancer development, and test its utility as a cancer biomarker.

MSMB: A Prostate-Secreted Protein and Cancer Biomarker

Microseminoprotein-Beta (MSMB) also known as Prostate Secretory Protein 94 (PSP94) is a small secreted protein that is produced in enormous amounts by the epithelial cells of the prostate gland. It is one of the most abundant proteins in the seminal plasma. The exact physiological role of MSMB is not known, but it is believed to play a role in anti-microbial and anti-inflammatory processes. In cancer, MSMB expression is frequently and strongly downregulated in the prostate tumor. Common variants in or near MSMB that are associated with prostate cancer risk have also been identified by genome-wide association studies (GWAS), suggesting that MSMB is of great interest in prostate cancer research.

Alternative Names

MSMB; PSP-94; Prostate Secreted Seminal Plasma Protein; Prostate Secretory Protein Of 94 Amino Acids; MSP; PSP; HPC13

Background

The protein encoded by this gene is a member of the immunoglobulin binding factor family. It is synthesized by the epithelial cells of the prostate gland and secreted into the seminal plasma. This protein has inhibin-like activity. It may have a role as an autocrine paracrine factor in uterine, breast and other female reproductive tissues. The expression of the encoded protein is found to be decreased in prostate cancer. Two alternatively spliced transcript variants encoding different isoforms are described for this gene. The use of alternate polyadenylation sites has been found for this gene.

Anti-MSMB rAb Products

Creative Biolabs' anti-MSMB recombinant antibodies are highly specific and sensitive and have been validated for the consistent detection of MSMB/PSP94 protein in prostate tissue, seminal plasma, and serum. They are validated for essential applications including IHC to monitor its downregulation in prostate tumors and ELISA for measurement as a potential circulating biomarker.

Table 1. Featured anti-MSMB recombinant antibody products at Creative Biolabs.

Customer Reviews

rAb Production

Creative Biolabs uses state-of-the-art production technologies to support the research community in the study of prostate cancer. Our anti-MSMB recombinant antibodies are produced in well-optimized mammalian cell lines to ensure correct folding and the recognition of the native secreted protein.

Featured Anti-MSMB Recombinant Antibody Production Platforms
Fig.1 Milligram-scale anti-MSMB recombinant antibody production.

Fig.2 Gram-scale anti-MSMB recombinant antibody production.

rAb Modalities

Creative Biolabs is dedicated to providing the research community with flexible and innovative tools. We offer anti-MSMB recombinant antibodies in a range of customizable modalities, including matched antibody pairs for the development of sensitive ELISAs, to help researchers worldwide study this protein.

Fig.3 Full-length anti-MSMB recombinant antibody production and modalities.

Take the next steps in the research of prostate cancer with Creative Biolabs' top-notch anti-MSMB recombinant antibodies. The strength of our portfolio lies in the high specificity, thorough validation, and unmatched consistency of our reagents, providing you with the best tools for your biomarker and fundamental biology studies. We have the expertise you can trust to support your important work. Contact our experts today.