MTHFD2

Recombinant Antibody Products Formats

Anti-MTHFD2 Recombinant Antibody Products

Recombinant Mouse Anti-Human MTHFD2 Antibody (MOB-0935MZ)
- Species Reactivity: Human
- Type: Mouse antibody
- Application: IHC-P
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Mouse Anti-MTHFD2 (C-Terminus) Recombinant Antibody (VS3-CJ645) (VS3-CJ645)
- Species Reactivity: Human, Mouse
- Type: Mouse IgG1, κ
- Application: WB
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Recombinant Mouse Anti-MTHFD2 Antibody (VS-0923-FY114) (VS-0923-FY114)
- Species Reactivity: Human
- Type: Mouse IgG1
- Application: ELISA, WB
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Anti-MTHFD2 Immunohistochemistry Kit (VS-0325-XY1389)
- Species Reactivity: Human, Mouse, Rat
- Target: MTHFD2
- Application: IHC
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Chicken Anti-MTHFD2 Polyclonal IgY (BRD-0377MZ)
- Species Reactivity: Human, Mouse
- Type: Chicken antibody
- Application: WB
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For Research Use Only. Not For Clinical Use.

This gene encodes a nuclear-encoded mitochondrial bifunctional enzyme with methylenetetrahydrofolate dehydrogenase and methenyltetrahydrofolate cyclohydrolase activities. The enzyme functions as a homodimer and is unique in its absolute requirement for magnesium and inorganic phosphate. Formation of the enzyme-magnesium complex allows binding of NAD. Alternative splicing results in two different transcripts, one protein-coding and the other not protein-coding. This gene has a pseudogene on chromosome 7. [provided by RefSeq, Mar 2009]

Protein class

Enzymes, Metabolic proteins

Predicted location

Intracellular

Single cell type specificity

Cell type enhanced (Langerhans cells, Smooth muscle cells, monocytes)

Immune cell specificity

Low immune cell specificity

Cell line specificity

Low cell line specificity

Interaction

Homodimer.