MTMR2

Antibody Magnetic Beads AbPlus Recombinant Antibody Products Formats

Anti-MTMR2 Recombinant Antibody Products

Recombinant Mouse Anti-Human MTMR2 Antibody (MOB-0940MZ)
- Species Reactivity: Human
- Type: Mouse antibody
- Application: WB
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AbPlus™ Anti-MTMR2 Magnetic Beads (VS-0724-YC80) (VS-0724-YC80)
- Target: MTMR2
- Target Species: Human
- Application: IP, Protein Purification
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Chicken Anti-MTMR2 Polyclonal IgY (BRD-0378MZ)
- Species Reactivity: Human
- Type: Chicken antibody
- Application: WB
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For Research Use Only. Not For Clinical Use.

This gene is a member of the myotubularin family of phosphoinositide lipid phosphatases. The encoded protein possesses phosphatase activity towards phosphatidylinositol-3-phosphate and phosphatidylinositol-3,5-bisphosphate. Mutations in this gene are a cause of Charcot-Marie-Tooth disease type 4B, an autosomal recessive demyelinating neuropathy. Alternatively spliced transcript variants encoding multiple isoforms have been found for this gene. [provided by RefSeq, Aug 2011]

Protein class

Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets

Predicted location

Intracellular

Single cell type specificity

Cell type enhanced (Oligodendrocytes, Late spermatids)

Immune cell specificity

Low immune cell specificity

Cell line specificity

Low cell line specificity

Interaction

Homodimer (via coiled-coil domain) (PubMed:12668758, PubMed:15998640). Heterotetramer consisting of one MTMR2 dimer and one SBF2/MTMR13 dimer (PubMed:15998640). Heterodimer with SBF1/MTMR5 (PubMed:12668758, PubMed:21372139). Heterodimer with MTMR12 (PubMed:12847286).

Molecular function

Hydrolase

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