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MTRR
Loading...Anti-MTRR Products
- AbPlus™ Anti-MTRR Magnetic Beads (VS-0724-YC141) (VS-0724-YC141)
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- Target: MTRR
- Target Species: Human
- Application: IP, Protein Purification
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More Infomation
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For Research Use Only. Not For Clinical Use.
Background
This gene encodes a member of the ferredoxin-NADP(+) reductase (FNR) family of electron transferases. This protein functions in the synthesis of methionine by regenerating methionine synthase to a functional state. Because methionine synthesis requires methyl-group transfer by a folate donor, activity of the encoded enzyme is important for folate metabolism and cellular methylation. Mutations in this gene can cause homocystinuria-megaloblastic anemia, cbl E type. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Dec 2015]
Protein class
Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets
Predicted location
Intracellular
Single cell type specificity
Cell type enhanced (Late spermatids, Alveolar cells type 2)
Immune cell specificity
Low immune cell specificity
Cell line specificity
Low cell line specificity
Interaction
Forms a multiprotein complex with MMACHC, MMADHC AND MTR.
Molecular function
Oxidoreductase
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