+ Filter
Loading...
MYBL2
Anti-MYBL2 Recombinant Antibody Products
- Recombinant Mouse Anti-Human MYBL2 Antibody (MOB-0875MZ)
-
- Species Reactivity: Human
- Type: Mouse antibody
- Application: ELISA, WB
Compare
-
- Derivation: Phage display library screening
- Species Reactivity: Human
- Type: IgG
- Application: WB, IHC, ICC, IP
Compare
- Anti-MYBL2 Immunohistochemistry Kit (VS-0325-XY1400)
-
- Species Reactivity: Human
- Target: MYBL2
- Application: IHC
Compare
More Infomation
Can't find the products you're looking for? Try to filter in the left sidebar.Filter By Tag
More Infomation
Our customer service representatives are available 24 hours a day, from Monday to Sunday. Contact Us
For Research Use Only. Not For Clinical Use.
The protein encoded by this gene, a member of the MYB family of transcription factor genes, is a nuclear protein involved in cell cycle progression. The encoded protein is phosphorylated by cyclin A/cyclin-dependent kinase 2 during the S-phase of the cell cycle and possesses both activator and repressor activities. It has been shown to activate the cell division cycle 2, cyclin D1, and insulin-like growth factor-binding protein 5 genes. Two transcript variants encoding different isoforms have been found for this gene.
Protein class
Cancer-related genes, Transcription factors
Predicted location
Intracellular
Single cell type specificity
Cell type enhanced (Plasma cells, Erythroid cells, Spermatogonia, B-cells, dendritic cells, Extravillous trophoblasts)
Immune cell specificity
Immune cell enriched (plasmacytoid DC)
Cell line specificity
Cell line enhanced (MCF7)
Interaction
Component of the DREAM complex (also named LINC complex) at least composed of E2F4, E2F5, LIN9, LIN37, LIN52, LIN54, MYBL1, MYBL2, RBL1, RBL2, RBBP4, TFDP1 and TFDP2. The complex exists in quiescent cells where it represses cell cycle-dependent genes. It dissociates in S phase when LIN9, LIN37, LIN52 and LIN54 form a subcomplex that binds to MYBL22. Interacts with CCNF (via the Cyclin N-terminal domain) (PubMed:25557911).
Molecular function
DNA-binding
More Types Infomation