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MYCBP
Loading...Anti-MYCBP Products
- Anti-MYCBP Immunohistochemistry Kit (VS-0325-XY1401)
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- Species Reactivity: Human, Mouse, Rat
- Target: MYCBP
- Application: IHC
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For Research Use Only. Not For Clinical Use.
The protein encoded by this gene binds to the N-terminus of the oncogenic protein C-MYC, enhancing the ability of C-MYC to activate E box-dependent transcription. The encoded protein is normally found in the cytoplasm, but it translocates to the nucleus during S phase of the cell cycle and associates with C-MYC. This protein may be involved in spermatogenesis. This gene can be silenced by microRNA-22. Two transcript variants, one protein-coding and the other probably not protein-coding, have been found for this gene.
Predicted location
Intracellular
Single cell type specificity
Cell type enhanced (Respiratory ciliated cells, Cytotrophoblasts)
Immune cell specificity
Low immune cell specificity
Cell line specificity
Low cell line specificity
Interaction
Binds via its C-terminal region to the N-terminal region of MYC. Associates with AKAP1/S-AKAP84. Interacts with MYCBPAP. Interacts with CFAP91 (PubMed:12223483).
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