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MYL12A
Loading...Anti-MYL12A Products
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- Derivation: Phage display library screening
- Species Reactivity: Human
- Type: IgG
- Application: FC, ICC, WB
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- Anti-MYL12A Immunohistochemistry Kit (VS-0325-XY1418)
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- Species Reactivity: Human, Mouse, Rat
- Target: MYL12A
- Application: IHC
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For Research Use Only. Not For Clinical Use.
This gene encodes a nonsarcomeric myosin regulatory light chain. This protein is activated by phosphorylation and regulates smooth muscle and non-muscle cell contraction. This protein may also be involved in DNA damage repair by sequestering the transcriptional regulator apoptosis-antagonizing transcription factor (AATF)/Che-1 which functions as a repressor of p53-driven apoptosis. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 8.
Predicted location
Intracellular
Single cell type specificity
Cell type enhanced (Cardiomyocytes)
Immune cell specificity
Low immune cell specificity
Cell line specificity
Low cell line specificity
Interaction
Myosin is a hexamer of 2 heavy chains and 4 light chains.
Molecular function
Motor protein, Muscle protein, Myosin
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