Mycobacterium kansasii Ag85B

Mycobacterium kansasii Ag85B is an antigenic protein of Mycobacterium kansasii, a non-tuberculous Mycobacterium that can cause respiratory infections. Ag85B belongs to the Ag85 protein family, involved in bacterial cell wall synthesis (e.g., mycolic acid metabolism). It has strong immunogenicity, inducing host cellular and humoral immune responses. Ag85B is a marker for Mycobacterium kansasii infection diagnosis and a candidate antigen for vaccines, as targeting it may help the host clear the bacterium and prevent infection progression.