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N4BP1

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For Research Use Only. Not For Clinical Use.


Background

Predicted to enable RNA nuclease activity; mRNA binding activity; and ubiquitin binding activity. Involved in cellular response to UV; negative regulation of macromolecule metabolic process; and regulation of innate immune response. Located in PML body; cytosol; and nucleolus. Orthologous to human N4BP1 (NEDD4 binding protein 1).
Predicted location

Intracellular

Single cell type specificity

Cell type enhanced (Alveolar cells type 1, Glandular and luminal cells)

Immune cell specificity

Immune cell enriched (neutrophil)

Cell line specificity

Low cell line specificity

Interaction

Interacts with NEDD4. Interacts with ITCH (via WW domain 2).

Molecular function

Hydrolase, Nuclease, RNA-binding

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