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NDN

Anti-NDN Products

Mouse Anti-NDN Recombinant Antibody (clone 28A12) (MOB-2303z)
- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG2a, κ
- Application: WB, ELISA, IF, IHC, IP
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Recombinant Mouse Anti-Human NDN Antibody (MOB-1327MZ)
- Species Reactivity: Human
- Type: Mouse antibody
- Application: IHC-P, WB
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Anti-NDN Immunohistochemistry Kit (VS-0525-XY4722)
- Species Reactivity: Human
- Target: NDN
- Application: IHC
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For Research Use Only. Not For Clinical Use.

This intronless gene is located in the Prader-Willi syndrome deletion region. It is an imprinted gene and is expressed exclusively from the paternal allele. Studies in mouse suggest that the protein encoded by this gene may suppress growth in postmitotic neurons.

Protein class

Human disease related genes, Plasma proteins

Predicted location

Intracellular

Single cell type specificity

Cell type enhanced (Leydig cells, Peritubular cells, Theca cells)

Immune cell specificity

Immune cell enhanced (plasmacytoid DC)

Cell line specificity

Cell line enhanced (AF22, ASC diff, HSkMC, NTERA-2, SuSa, U-2 OS, U-266/70, U-266/84)

Interaction

Binds to the transactivation domains of E2F1 and p53. Binds also SV40 large T antigen and adenovirus E1A. Interacts with nucleobindin 1 and 2 (By similarity).

Molecular function

DNA-binding

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