Anti-NDST1 Products

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For Research Use Only. Not For Clinical Use.

Unlocking the mysteries of glycobiology and developmental biology has never been easier with Creative Biolabs' elite line of anti-NDST1 recombinant antibodies. A primary enzyme responsible for Heparan sulfate biosynthesis, N-deacetylase and N-sulfotransferase 1 (NDST1) is crucial for cell signaling and tissue development. Equipped with a Creative Biolabs high-quality recombinant antibody to NDST1, you can explore growth factor signaling, cancer progression and inflammatory processes with confidence.

NDST1: A Key Modifying Enzyme in Heparan Sulfate Biosynthesis

Located in the Golgi apparatus, N-deacetylase and N-sulfotransferase 1 (NDST1) is a bifunctional enzyme responsible for an early modification step during the biosynthesis of heparan sulfate proteoglycans (HSPGs). This essential sulfotransferase first removes the acetyl group from N-acetylglucosamine residues and then transfers a sulfate group in its place. The overall structure of the heparan sulfate chain is crucial to its ability to bind and regulate the activities of many signaling molecules, including growth factors (FGF and HGF), chemokines and morphogens. Therefore, NDST1 functions as a master regulator of development, angiogenesis and inflammation.

Alternative Names

HSST; NST1; MRT46

Background

The gene encodes a member of the heparan sulfate/heparin GlcNAc N-deacetylase/ N-sulfotransferase family. The encoded enzyme is a type II transmembrane protein that is localized in the Golgi apparatus. The encoded protein transfers sulfate from 3'-phosphoadenosine 5'-phosphosulfate to the nitrogen of glucosamine in heparan sulfate. Alternative splicing results in multiple transcript variants.

Anti-NDST1 rAb Products

Our anti-NDST1 recombinant antibodies are meticulously engineered for high specificity and outstanding performance. Each lot is rigorously validated to ensure accurate detection of the target NDST1 enzyme without cross-reactivity with other NDST isoforms. Optimized for Western Blot and immunofluorescence applications for Golgi localization studies, these rAbs are the reliable tools you need to take your glycobiology research to the next level.

Table 1. Featured anti-NDST1 recombinant antibody products at Creative Biolabs.

Customer Reviews

rAb Production

Creative Biolabs leverages the latest technology in antibody production to support glycobiology research. Our anti-NDST1 recombinant antibodies are produced in expression systems that have been optimized to generate antibodies that recognize and bind to the native enzyme, ensuring a highly specific and active reagent for your experiments.

Featured Anti-NDST1 Recombinant Antibody Production Platforms
Fig.1 Milligram-scale anti-NDST1 recombinant antibody production.

Fig.2 Gram-scale anti-NDST1 recombinant antibody production.

rAb Modalities

Creative Biolabs is committed to empowering your scientific breakthroughs with flexible and customizable antibody solutions. Our anti-NDST1 recombinant antibodies are available in a variety of formats, tailored to meet the unique requirements of your experiments. Researchers across the globe trust Creative Biolabs recombinant antibodies to help unlock the mysteries of NDST1.

Fig.3 Full-length anti-NDST1 recombinant antibody production and modalities.

Creative Biolabs recombinant antibodies are the perfect choice for unraveling the complex functions of NDST1 in Heparan sulfate synthesis. Defined by their unparalleled specificity and extensive validation, you can trust Creative Biolabs to supply you with the ideal tools for your research. Connect with our experts today and experience quality that will accelerate your discovery.