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NDST1
Anti-NDST1 Recombinant Antibody Products
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG2a, κ
- Application: WB, IHC, ELISA
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- Recombinant Mouse Anti-Human NDST1 Antibody (MOB-1314MZ)
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- Species Reactivity: Human
- Type: Mouse antibody
- Application: IHC-P, WB
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For Research Use Only. Not For Clinical Use.
This gene encodes a member of the heparan sulfate/heparin GlcNAc N-deacetylase/ N-sulfotransferase family. The encoded enzyme is a type II transmembrane protein that resides in the Golgi apparatus. The encoded protein catalyzes the transfer of sulfate from 3'-phosphoadenosine 5'-phosphosulfate to nitrogen of glucosamine in heparan sulfate. Alternative splicing results in multiple transcript variants.
Protein class
Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets
Predicted location
Intracellular, Membrane (different isoforms)
Single cell type specificity
Cell type enhanced (Hepatocytes)
Immune cell specificity
Group enriched (classical monocyte, neutrophil, non-classical monocyte, myeloid DC, eosinophil, intermediate monocyte, basophil)
Cell line specificity
Low cell line specificity
Interaction
Monomer. [Isoform 1]: Interacts with heparan sulfate co-polymerase subunits EXT1 and EXT2. Interacts with NDST1 isoform 3. [Isoform 3]: Interacts with heparan sulfate co-polymerase subunits EXT1 and EXT2. Interacts with NDST1 isoform 1.
Molecular function
Hydrolase, Multifunctional enzyme, Transferase
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