NF-kB Nuclear Translocation

NF-κB (Nuclear Factor kappa-light-chain-enhancer of activated B cells) is a family of ubiquitous and inducible transcription factors that serve as central regulators of a vast array of cellular processes, including innate and adaptive immunity, inflammation, cell proliferation, stress responses, and apoptosis. The activity of NF-κB is tightly controlled, primarily through its nuclear translocation, a crucial step that allows it to access and regulate gene expression in the nucleus.