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NR2C1
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- Human Anti-NR2C1 Recombinant Antibody (HPAB-1793-FY) (HPAB-1793-FY)
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- Species Reactivity: Human
- Type: Human IgG
- Application: WB, ELISA
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- Human Anti-NR2C1 Recombinant Antibody (HPAB-1794-FY) (HPAB-1794-FY)
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- Species Reactivity: Human
- Type: Human IgG
- Application: WB, ELISA
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- Human Anti-NR2C1 Recombinant Antibody (HPAB-1795-FY) (HPAB-1795-FY)
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- Species Reactivity: Human
- Type: Human IgG
- Application: WB, ELISA
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- Mouse Anti-NR2C1 Recombinant Antibody (HPAB-1796-FY) (HPAB-1796-FY)
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- Species Reactivity: Human
- Type: Mouse IgG1
- Application: WB, ELISA
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- Human Anti-NR2C1 Recombinant Antibody; Fab Fragment (HPAB-1793-FY-F(E)) (HPAB-1793-FY-F(E))
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- Species Reactivity: Human
- Type: Human Fab
- Application: WB, ELISA
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- Mouse Anti-NR2C1 Recombinant Antibody; scFv Fragment (HPAB-1796-FY-S(P)) (HPAB-1796-FY-S(P))
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- Species Reactivity: Human
- Type: Mouse scFv
- Application: WB, ELISA
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- Human Anti-NR2C1 Recombinant Antibody; Fab Fragment (HPAB-1794-FY-F(E)) (HPAB-1794-FY-F(E))
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- Species Reactivity: Human
- Type: Human Fab
- Application: WB, ELISA
Compare
- Human Anti-NR2C1 Recombinant Antibody; Fab Fragment (HPAB-1795-FY-F(E)) (HPAB-1795-FY-F(E))
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- Species Reactivity: Human
- Type: Human Fab
- Application: WB, ELISA
Compare
- Mouse Anti-NR2C1 Recombinant Antibody; Fab Fragment (HPAB-1796-FY-F(E)) (HPAB-1796-FY-F(E))
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- Species Reactivity: Human
- Type: Mouse Fab
- Application: WB, ELISA
Compare
- Human Anti-NR2C1 Recombinant Antibody; scFv Fragment (HPAB-1793-FY-S(P)) (HPAB-1793-FY-S(P))
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- Species Reactivity: Human
- Type: Human scFv
- Application: WB, ELISA
Compare
- Human Anti-NR2C1 Recombinant Antibody; scFv Fragment (HPAB-1794-FY-S(P)) (HPAB-1794-FY-S(P))
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- Species Reactivity: Human
- Type: Human scFv
- Application: WB, ELISA
Compare
- Human Anti-NR2C1 Recombinant Antibody; scFv Fragment (HPAB-1795-FY-S(P)) (HPAB-1795-FY-S(P))
-
- Species Reactivity: Human
- Type: Human scFv
- Application: WB, ELISA
Compare
- Anti-NR2C1 Immunohistochemistry Kit (VS-0525-XY4949)
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- Species Reactivity: Human
- Target: NR2C1
- Application: IHC
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- Anti-Mouse NR2C1 Immunohistochemistry Kit (VS-0525-XY4950)
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- Species Reactivity: Human, Mouse, Rat
- Target: NR2C1
- Application: IHC
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For Research Use Only. Not For Clinical Use.
This gene encodes a nuclear hormone receptor characterized by a highly conserved DNA binding domain (DBD), a variable hinge region, and a carboxy-terminal ligand binding domain (LBD) that is typical for all members of the steroid/thyroid hormone receptor superfamily.
Protein class
Nuclear receptors, Plasma proteins, Transcription factors
Predicted location
Intracellular
Single cell type specificity
Low cell type specificity
Immune cell specificity
Low immune cell specificity
Cell line specificity
Low cell line specificity
Interaction
Homodimer (By similarity). Heterodimer; binds DNA as a heterodimer with NR2C2 required for chromatin remodeling and for binding to promoter regions such as globin DR1 repeats (By similarity). Interacts with NRIP1 (via its LXXLL motifs); the interaction provides corepressor activity. Interacts with HDAC3 (via the DNA-binding domain). Interacts with HDAC4 (via the DNA-binding domain). Interacts with PIAS1; the interaction is required for sumoylation of NR2C1. Interacts with UBE2I; the interaction is required for sumoylation of NR2C1. Interacts with KAT2B; the interaction acts as a corepressor of gene expression (By similarity). Interacts with ESR1; the interaction prevents homodimerization of ESR1 and suppresses its transcriptional activity and cell growth.
Molecular function
Activator, DNA-binding, Receptor, Repressor
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