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NR2F1
Loading...Anti-NR2F1 Products
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- Derivation: Phage display library screening
- Species Reactivity: Mouse, Rat, Human
- Type: IgG
- Application: WB, IHC-P, ICC/IF, FC
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- Anti-NR2F1 Immunohistochemistry Kit (VS-0525-XY4955)
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- Species Reactivity: Human
- Target: NR2F1
- Application: IHC
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- Anti-Mouse NR2F1 Immunohistochemistry Kit (VS-0525-XY4956)
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- Species Reactivity: Human, Mouse, Rat
- Target: NR2F1
- Application: IHC
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For Research Use Only. Not For Clinical Use.
The protein encoded by this gene is a nuclear hormone receptor and transcriptional regulator. The encoded protein acts as a homodimer and binds to 5'-AGGTCA-3' repeats. Defects in this gene are a cause of Bosch-Boonstra optic atrophy syndrome (BBOAS). [provided by RefSeq, Apr 2014]
Protein class
Disease related genes, Human disease related genes, Nuclear receptors, Transcription factors
Predicted location
Intracellular
Single cell type specificity
Cell type enhanced (Endometrial stromal cells, Hepatic stellate cells, Leydig cells)
Immune cell specificity
Not detected in immune cells
Cell line specificity
Cell line enhanced (AF22, AN3-CA, HHSteC, hTERT-RPE1, PC-3)
Interaction
Binds DNA as dimer; homodimer and probable heterodimer with NR2F6 (PubMed:11682620). Interacts with GTF2B; this interaction is direct (PubMed:1517211). Interacts with COPS2 (PubMed:10207062).
Molecular function
Activator, DNA-binding, Receptor, Repressor
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