Anti-NR2F1 Products

Can't find the products you're looking for? Try to filter in the left sidebar.Filter By Tag

Our customer service representatives are available 24 hours a day, from Monday to Sunday. Contact Us

For Research Use Only. Not For Clinical Use.

Creative Biolabs specializes in providing advanced research reagents for developmental biology and neuroscience. Our recombinant antibodies against NR2F1 are top-tier and offer the highest quality. NR2F1 (also known as COUP-TF1) is a nuclear receptor with important roles in vision and brain development by regulating gene expression during embryonic and fetal stages. Our validated anti-NR2F1 antibodies are essential for studying its molecular etiology of Bosch-Boonstra-Schaaf optic atrophy and its role in neural differentiation.

NR2F1: A Master Regulator of Neurodevelopment

Nuclear Receptor Subfamily 2 Group F Member 1 (NR2F1) is a ligand-inducible transcription factor belonging to the steroid hormone receptor superfamily. NR2F1 is a key dose-dependent regulator of central nervous system development and is particularly important for the proper development of the visual system, including the optic nerve and visual cortex, as well as the hippocampus and peripheral nervous system. Haploinsufficiency of the NR2F1 gene results in Bosch-Boonstra-Schaaf optic atrophy, a rare complex neurodevelopmental disorder. Affected individuals have a combination of vision loss, intellectual disability, and features of autism.

Alternative Names

Nuclear Receptor Subfamily 2 Group F Member 1; COUP Transcription Factor I; V-ErbA-Related Protein 3; COUP-TF I; COUP-TF1; TFCOUP1; ERBAL3; EAR-3; EAR3; Transcription Factor COUP 1 (Chicken Ovalbumin Upstream Promoter 1, V-Erb-A Homolog-Like 3);

Background

The protein encoded by this gene is a nuclear hormone receptor and transcriptional regulator. The encoded protein acts as a homodimer and binds to 5'-AGGTCA-3' repeats. Defects in this gene are a cause of Bosch-Boonstra optic atrophy syndrome (BBOAS). [provided by RefSeq, Apr 2014]

Anti-NR2F1 rAb Products

Creative Biolabs’ anti-NR2F1 recombinant antibodies (rAbs) are designed for exceptional specificity and performance. They are carefully validated to robustly detect NR2F1 protein in nuclear extracts. They are optimized for applications such as Western Blot to measure expression levels, IHC in developing brain tissue, and Chromatin Immunoprecipitation (ChIP) to uncover its target genes. Our rAbs are the tools of choice for developmental biologists.

Table 1. Featured anti-NR2F1 recombinant antibody products at Creative Biolabs.

Customer Reviews

rAb Production

Creative Biolabs is driving progress in developmental biology with advanced production technologies. Our anti-NR2F1 recombinant antibodies are carefully designed and screened to provide high-affinity recognition for this important nuclear receptor, making them ideal for the most challenging applications.

Featured Anti-NR2F1 Recombinant Antibody Production Platforms
Fig.1 Milligram-scale anti-NR2F1 recombinant antibody production.

Fig.2 Gram-scale anti-NR2F1 recombinant antibody production.

rAb Modalities

Creative Biolabs is dedicated to offering versatile and innovative tools to support the needs of the research community. Our anti-NR2F1 antibodies are offered in a range of modalities to enable a variety of experimental approaches, empowering researchers around the world to study this important transcription factor.

Fig.3 Full-length anti-NR2F1 recombinant antibody production and modalities.

Accelerate progress in your neurodevelopmental research with Creative Biolabs’ superior anti-NR2F1 recombinant antibodies. Our portfolio stands out for its exceptional specificity and validation in nuclear applications. Put our expertise to work for your important research. Contact our experts today.