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NRF1
Anti-NRF1 Recombinant Antibody Products
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- Species Reactivity: Human, Mouse, Rat
- Type: Rabbit IgG
- Application: WB, IF, IHC, FC, IP
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG2a
- Application: WB
- Mouse Anti-NRF1 Recombinant Antibody (clone 1G1) (VS3-XY1184)
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- Species Reactivity: Human
- Type: Mouse IgG1
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- Species Reactivity: Human, Mouse, Rat
- Type: Rabbit IgG
- Application: WB, IHC-Fr, IHC-P, ICC, IF, IP
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- Species Reactivity: Human
- Application: IHC-P, WB
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- Derivation: Phage display library screening
- Species Reactivity: Mouse, Rat, Human
- Type: IgG
- Application: WB, ICC/IF, FC, IP, IHC-P
- Anti-NRF1 Immunohistochemistry Kit (VS-0325-XY1520)
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- Species Reactivity: Human, Mouse
- Target: NRF1
- Application: IHC
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For Research Use Only. Not For Clinical Use.
This gene encodes a protein that homodimerizes and functions as a transcription factor which activates the expression of some key metabolic genes regulating cellular growth and nuclear genes required for respiration, heme biosynthesis, and mitochondrial DNA transcription and replication. The protein has also been associated with the regulation of neurite outgrowth. Alternative splicing results in multiple transcript variants. Confusion has occurred in bibliographic databases due to the shared symbol of NRF1 for this gene and for "nuclear factor (erythroid-derived 2)-like 1" which has an official symbol of NFE2L1. [provided by RefSeq, May 2014]
Protein class
Metabolic proteins, Transcription factors
Predicted location
Intracellular
Single cell type specificity
Group enriched (Oligodendrocyte precursor cells, Astrocytes, Oligodendrocytes, Excitatory neurons, Inhibitory neurons, Microglial cells)
Immune cell specificity
Low immune cell specificity
Cell line specificity
Low cell line specificity
Interaction
Homodimer. Binds DNA as a dimer. Interacts with PPRC1.
Molecular function
Activator, DNA-binding
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