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NT5M

This gene encodes a 5 nucleotidase that localizes to the mitochondrial matrix. This enzyme dephosphorylates the 5- and 2(3)-phosphates of uracil and thymine deoxyribonucleotides. The gene is located within the Smith-Magenis syndrome region on chromosome 17. [provided by RefSeq, Jul 2008]
Protein class

Metabolic proteins

Predicted location

Intracellular

Single cell type specificity

Cell type enhanced (Erythroid cells, Distal tubular cells, Horizontal cells, Inhibitory neurons)

Immune cell specificity

Immune cell enhanced (eosinophil)

Cell line specificity

Cell line enhanced (JURKAT, RPMI-8226, U-266/70)

Interaction

Homodimer.

Molecular function

Hydrolase

More Types Infomation

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