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NUDC

Anti-NUDC Products
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- Species Reactivity: Human
- Application: WB
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- Species Reactivity: Human, Mouse, Rat
- Type: Rabbit IgG
- Application: ELISA, WB
- AbPlus™ Anti-NUDC Magnetic Beads (VS-0724-YC670) (VS-0724-YC670)
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- Target: NUDC
- Target Species: Human
- Application: IP, Protein Purification
- Anti-NUDC Immunohistochemistry Kit (VS-0525-XY5031)
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- Species Reactivity: Human
- Target: NUDC
- Application: IHC
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- Derivation: Phage display library screening
- Species Reactivity: Human
- Type: IgG
- Application: WB, IP, IHC-P, ICC, FC
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For Research Use Only. Not For Clinical Use.
Background
This gene encodes a nuclear distribution protein that plays an essential role in mitosis and cytokinesis. The encoded protein is involved in spindle formation during mitosis and in microtubule organization during cytokinesis. Pseudogenes of this gene are found on chromosome 2. [provided by RefSeq, Feb 2012]
Predicted location
Intracellular, Membrane (different isoforms)
Single cell type specificity
Cell type enhanced (Hepatocytes, Respiratory ciliated cells)
Immune cell specificity
Low immune cell specificity
Cell line specificity
Low cell line specificity
Interaction
Interacts with PAFAH1B1 (By similarity). Interacts with PLK1 (PubMed:12852857). Part of a complex containing PLK1, NUDC, dynein and dynactin (PubMed:12852857). Interacts with DCDC1 (PubMed:22159412). Interacts with EML4 (via WD repeats) (PubMed:25789526).
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