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OXCT1

Anti-OXCT1 Recombinant Antibody Products

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For Research Use Only. Not For Clinical Use.


This gene encodes a member of the 3-oxoacid CoA-transferase gene family. The encoded protein is a homodimeric mitochondrial matrix enzyme that plays a central role in extrahepatic ketone body catabolism by catalyzing the reversible transfer of coenzyme A from succinyl-CoA to acetoacetate. Mutations in this gene are associated with succinyl CoA:3-oxoacid CoA transferase deficiency. [provided by RefSeq, Jul 2008]
Protein class

Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets

Predicted location

Intracellular

Single cell type specificity

Cell type enhanced (Cardiomyocytes, Distal tubular cells)

Immune cell specificity

Low immune cell specificity

Cell line specificity

Cell line enhanced (HeLa, SiHa)

Interaction

Homodimer (PubMed:10964512, PubMed:23420214). Only one subunit is competent to transfer the CoA moiety to the acceptor carboxylate (3-oxo acid) (By similarity).

Molecular function

Transferase

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