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OXCT1
Loading...Anti-OXCT1 Products
- AbPlus™ Anti-OXCT1 Magnetic Beads (VS-0724-YC412) (VS-0724-YC412)
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- Target: OXCT1
- Target Species: Human
- Application: IP, Protein Purification
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- Recombinant Anti-Human OXCT1 Antibody Fab Fragment (MOB-2751z-F(E))
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Fab
- Application: ELISA, IP, FuncS
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- Recombinant Anti-Human OXCT1 Antibody scFv Fragment (MOB-2751z-S(P))
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- Derivation: Mouse
- Species Reactivity: Human
- Type: scFv
- Application: IP, IF, Biosensors, FuncS
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- Anti-OXCT1 Immunohistochemistry Kit (VS-0325-XY1547)
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- Species Reactivity: Human, Mouse, Rat
- Target: OXCT1
- Application: IHC
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More Infomation
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For Research Use Only. Not For Clinical Use.
Background
This gene encodes a member of the 3-oxoacid CoA-transferase gene family. The encoded protein is a homodimeric mitochondrial matrix enzyme that plays a central role in extrahepatic ketone body catabolism by catalyzing the reversible transfer of coenzyme A from succinyl-CoA to acetoacetate. Mutations in this gene are associated with succinyl CoA:3-oxoacid CoA transferase deficiency. [provided by RefSeq, Jul 2008]
Protein class
Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets
Predicted location
Intracellular
Single cell type specificity
Cell type enhanced (Cardiomyocytes, Distal tubular cells)
Immune cell specificity
Low immune cell specificity
Cell line specificity
Cell line enhanced (HeLa, SiHa)
Interaction
Homodimer (PubMed:10964512, PubMed:23420214). Only one subunit is competent to transfer the CoA moiety to the acceptor carboxylate (3-oxo acid) (By similarity).
Molecular function
Transferase
More Types Infomation