PHB
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Loading...- Recombinant Human Anti-Polyhydroxybutyrate Antibody Fab Fragment (PABX-156-F (E))
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- Derivation: Human
- Type: Fab
- Application: WB, ELISA, IF, FuncS
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- Rabbit Anti-PHB Polyclonal Antibody (MRO-2134-CN) (MRO-2134-CN)
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- Species Reactivity: Human, Mouse, Rat
- Type: Rabbit IgG
- Application: WB, IF, IHC, FC
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- Species Reactivity: Human, Mouse, Rat, Zebrafish
- Type: Rabbit IgG
- Application: WB, IF, IHC, IP, FC
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- Recombinant Anti-PHB Antibody (MOB-767)
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- Derivation: Mouse
- Type: IgG
- Application: ELISA, WB, Neut, FuncS
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- Recombinant Human Anti-PHB Antibody (MHH-767)
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- Derivation: Human
- Type: IgG
- Application: IF, FC, FuncS
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- Recombinant Human Anti-Polyhydroxybutyrate Antibody scFv Fragment (PABX-156-S (P))
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- Derivation: Human
- Type: scFv
- Application: WB, ELISA, IF, FuncS
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- Human Anti-PHB Antibody, mRNA (PABX-156-mRNA)
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- Species Reactivity: Human
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- Mouse Anti-PHB Recombinant Antibody (VS3-CJ897) (VS3-CJ897)
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- Species Reactivity: Human, Mouse, Rat
- Type: Mouse IgG2b, κ
- Application: WB, IHC-P
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- Rabbit Anti-PHB Recombinant Antibody (VS3-CJ898) (VS3-CJ898)
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- Species Reactivity: Human, Mouse, Rat, Zebrafish
- Type: Rabbit IgG
- Application: WB, ICC, IHC, IP, FC
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- Derivation: Mouse
- Species Reactivity: Human, Mouse, Rat
- Type: Mouse IgG2b, κ
- Application: WB, IHC
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- AbPlus™ Anti-PHB Magnetic Beads (VS-0724-YC1299) (VS-0724-YC1299)
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- Target: PHB
- Target Species: Human
- Application: IP, Protein Purification
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- Recombinant Human Anti-PHB Antibody Fab Fragment (MHH-767-F(E))
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- Derivation: Human
- Type: Fab
- Application: WB, IF, FuncS
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- Recombinant Human Anti-PHB Antibody scFv Fragment (MHH-767-S(P))
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- Derivation: Human
- Type: scFv
- Application: IF, FC, Biosensors, FuncS
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- Recombinant Anti-PHB Antibody Fab Fragment (MOB-767-F(E))
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- Derivation: Mouse
- Type: Fab
- Application: FC, Neut, Funcs
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- Recombinant Anti-PHB Antibody scFv Fragment (MOB-767-S(P))
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- Derivation: Mouse
- Type: scFv
- Application: WB, IHC, FuncS
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- Mouse Anti-PHB Monoclonal Antibody (clone 5H7) (VS7-0425-WR601)
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- Species Reactivity: Human, Mouse, Rat, Monkey
- Type: Mouse IgG1
- Application: WB, IHC, ICC, FC
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- AibGenesis™ Rabbit Anti-PHB Recombinant Antibody (AibG-Rb-PH645) (VS-0426-FY645)
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- Species Reactivity: Human, Mouse, Rat
- Type: Rabbit IgG, Kappa
- Application: WB, IHC, ICC, IF, ELISA, IP
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- Derivation: Phage display library screening
- Species Reactivity: Human
- Type: IgG
- Application: WB, IP, IHC-P, ICC, FC
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- Mouse Anti-PHB Monoclonal Antibody (VS7-0425-WR602) (VS7-0425-WR602)
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- Species Reactivity: Human, Mouse, Rat, Monkey
- Type: Mouse IgG
- Application: WB, IHC-P, IF, ICC, FC, ELISA
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For Research Use Only. Not For Clinical Use.
Background
A highly conserved protein primarily localized to the inner mitochondrial membrane. It functions as a molecular chaperone to stabilize mitochondrial proteins and maintain cristae structure. It also plays roles in cell cycle regulation, apoptosis, and serves as a putative tumor suppressor.
Protein class
Plasma proteins
Predicted location
Intracellular
Single cell type specificity
Cell type enhanced (Proximal tubular cells)
Immune cell specificity
Low immune cell specificity
Cell line specificity
Cell line enhanced (CACO-2)
Interaction
The mitochondrial prohibitin complex consists of two subunits (PHB1 and PHB2), assembled into a membrane-associated ring-shaped supercomplex of approximately 1 mDa (PubMed:11302691, 20959514, 28017329, 31522117). Interacts with STOML2 (PubMed:21746876). Interacts with MAP1LC3B (membrane-bound form LC3-II); the interaction requires PHB2 and takes place upon Parkin-mediated mitochondrial damage (PubMed:28017329). Interacts with STAT3 (unphosphorylated or phosphorylated at 'Ser-727') (PubMed:31899195). Interacts with CLPB (PubMed:31522117). Interacts with CD86 (via cytoplasmic domain); the interactions increases after priming with CD40 (By similarity). (Microbial infection) Interacts with SARS coronavirus/SARS-CoV nsp2 protein. (Microbial infection) Interacts with chikungunya virus spike glycoprotein E2. (Microbial infection) Interaction with human immunodeficiency virus type 1/HIV-1 envelope glycoprotein GP160. (Microbial infection) Interacts with human enterovirus 71/EV-71 capsid protein VP0, protein 3CD and protease 3C.
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