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PI3
Loading...Anti-PI3 Products
- Mouse Anti-PI3 Recombinant Antibody (clone 44B2) (MOB-3929z)
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG1, κ
- Application: WB, IP, IF, ELISA
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- Anti-PI-3 Antibody LS-C394233 (MOB-0320MC)
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- Species Reactivity: Ascaris suum (tested or 100% immunogen sequence identity)
- Application: ELISA
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- Derivation: Phage display library screening
- Species Reactivity: Human
- Type: IgG
- Application: WB
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- Anti-PI3 Immunohistochemistry Kit (VS-0525-XY5384)
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- Species Reactivity: Human
- Target: PI3
- Application: IHC
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For Research Use Only. Not For Clinical Use.
This gene encodes an elastase-specific inhibitor that functions as an antimicrobial peptide against Gram-positive and Gram-negative bacteria, and fungal pathogens. The protein contains a WAP-type four-disulfide core (WFDC) domain, and is thus a member of the WFDC domain family. Most WFDC gene members are localized to chromosome 20q12-q13 in two clusters: centromeric and telomeric. This gene belongs to the centromeric cluster. Expression of this gene is upgulated by bacterial lipopolysaccharides and cytokines.
Protein class
Plasma proteins
Predicted location
Secreted
Single cell type specificity
Group enriched (Basal respiratory cells, Club cells)
Immune cell specificity
Immune cell enriched (neutrophil)
Cell line specificity
Group enriched (EFO-21, HaCaT, OE19, PC-3)
Molecular function
Protease inhibitor, Serine protease inhibitor
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