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PIGO
Anti-PIGO Recombinant Antibody Products
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- Species Reactivity: Human
- Application: WB
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For Research Use Only. Not For Clinical Use.
This gene encodes a protein that is involved in glycosylphosphatidylinositol (GPI)-anchor biosynthesis. The GPI-anchor is a glycolipid which contains three mannose molecules in its core backbone. The GPI-anchor is found on many blood cells and serves to anchor proteins to the cell surface. This protein is involved in the transfer of ethanolaminephosphate (EtNP) to the third mannose in GPI. At least three alternatively spliced transcripts encoding two distinct isoforms have been found for this gene. [provided by RefSeq, Jan 2011]
Protein class
Disease related genes, Human disease related genes, Metabolic proteins
Predicted location
Membrane
Single cell type specificity
Low cell type specificity
Immune cell specificity
Low immune cell specificity
Cell line specificity
Low cell line specificity
Interaction
Forms a complex with PIGF. PIGF is required to stabilize PIGO (By similarity).
Molecular function
Transferase
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