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PLA2G4A
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For Research Use Only. Not For Clinical Use.
Selectively hydrolyzes arachidonyl phospholipids in the sn-2 position releasing arachidonic acid. Together with its lysophospholipid activity, it is implicated in the initiation of the inflammatory response
Protein class
Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, RAS pathway related proteins
Predicted location
Intracellular
Single cell type specificity
Cell type enhanced (Microglial cells, Endometrial ciliated cells, Glandular and luminal cells)
Immune cell specificity
Group enriched (intermediate monocyte, eosinophil, myeloid DC, classical monocyte, non-classical monocyte, plasmacytoid DC)
Cell line specificity
Cell line enhanced (HeLa, OE19, RPMI-8226, U-2197)
Interaction
Interacts with KAT5.
Molecular function
Hydrolase
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