+ Filter
Loading...
PNKP
Loading...Anti-PNKP Products
-
- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG1, κ
- Application: WB, IP, IF, ELISA
Compare
- AbPlus™ Anti-PNKP Magnetic Beads (VS-0724-YC590) (VS-0724-YC590)
-
- Target: PNKP
- Target Species: Human
- Application: IP, Protein Purification
Compare
- Anti-PNKP Immunohistochemistry Kit (VS-0525-XY5522)
-
- Species Reactivity: Human
- Target: PNKP
- Application: IHC
Compare
View More Products
Can't find the products you're looking for? Try to filter in the left sidebar.Filter By Tag
More Infomation
Our customer service representatives are available 24 hours a day, from Monday to Sunday. Contact Us
For Research Use Only. Not For Clinical Use.
Background
This locus represents a gene involved in DNA repair. In response to ionizing radiation or oxidative damage, the protein encoded by this locus catalyzes 5' phosphorylation and 3' dephosphorylation of nucleic acids. Mutations at this locus have been associated with microcephaly, seizures, and developmental delay.
Protein class
Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets
Predicted location
Intracellular
Single cell type specificity
Low cell type specificity
Immune cell specificity
Low immune cell specificity
Cell line specificity
Low cell line specificity
Interaction
Monomer (By similarity). Interacts (via FHA domain) with XRCC4; mainly interacts with XRCC4 phosphorylated by CK2 but is also able to interact at much lower level with unphosphorylated PNKP (PubMed:15385968, 20852255, 28453785).
Molecular function
Hydrolase, Kinase, Multifunctional enzyme, Transferase
More Types Infomation
