POLG

Anti-POLG Products

Recombinant Rabbit Anti-POLG Antibody (clone R06-1G0) (VS3-FY1164)
- Species Reactivity: Human
- Type: Rabbit IgG
- Application: WB
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Hi-Affi™ Recombinant Rabbit Anti-POLG Monoclonal Antibody (DS2779AB) (MOR-2779)
- Derivation: Phage display library screening
- Species Reactivity: Human
- Type: IgG
- Application: WB
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For Research Use Only. Not For Clinical Use.

Background

POLG is located on the q arm of chromosome 15 in position 26.1 and has 23 exons. The POLG gene produces a 140 kDa protein composed of 1239 amino acids.

Protein class

Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets

Predicted location

Intracellular

Single cell type specificity

Low cell type specificity

Immune cell specificity

Low immune cell specificity

Cell line specificity

Low cell line specificity

Interaction

Interacts with C1QBP; the interaction results in nucleolar localization of C1QBP, probably due to prevention of C1QBP maturation and redirection from mitochondria to nucleoli.

Molecular function

DNA-binding, DNA-directed DNA polymerase, Nucleotidyltransferase, Transferase

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