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PPP1R13L

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For Research Use Only. Not For Clinical Use.


Protein class

Transcription factors

Predicted location

Intracellular

Single cell type specificity

Cell type enhanced (Syncytiotrophoblasts, Granulosa cells, Basal prostatic cells)

Immune cell specificity

Not detected in immune cells

Cell line specificity

Cell line enhanced (HBEC3-KT, hTCEpi, hTERT-HME1)

Interaction

Interacts with RELA NF-kappa-B subunit and with SP1 via its C-terminus part. Interacts (via SH3 domain and ANK repeats) with p53/TP53; the interaction inhibits pro-apoptotic activity of p53/TP53 (PubMed:12524540). Interacts with TP63 and TP73.

Molecular function

Repressor

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