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PPP1R9A

Anti-PPP1R9A Products

Recombinant Mouse anti-Human PPP1R9A Monoclonal antibody (EML1748) (MOB-0209CT)
- Species Reactivity: Human
- Application: WB
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Hi-Affi™ Recombinant Rabbit Anti-PPP1R9A Monoclonal Antibody (DS2824AB) (MOR-2824)
- Derivation: Phage display library screening
- Species Reactivity: Human
- Type: IgG
- Application: WB, FC
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For Research Use Only. Not For Clinical Use.

This gene is imprinted, and located in a cluster of imprinted genes on chromosome 7q12. This gene is transcribed in both neuronal and multiple embryonic tissues, and it is maternally expressed mainly in embryonic skeletal muscle tissues and biallelically expressed in other embryonic tissues. The protein encoded by this gene includes a PDZ domain and a sterile alpha motif (SAM). It is a regulatory subunit of protein phosphatase I, and controls actin cytoskeleton reorganization. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Protein class

Plasma proteins

Predicted location

Intracellular

Single cell type specificity

Cell type enhanced (Oligodendrocyte precursor cells, Oligodendrocytes, Astrocytes, Excitatory neurons, Inhibitory neurons)

Immune cell specificity

Group enriched (NK-cell, basophil)

Cell line specificity

Cell line enhanced (HAP1, RH-30)

Interaction

Possibly exists as a homodimer, homotrimer or a homotetramer. Interacts with F-actin, protein phosphatase 1 (PP1), neurabin-2 and p70-S6K (By similarity).

Molecular function

Actin-binding, Developmental protein

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