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PPP3R1
Anti-PPP3R1 Recombinant Antibody Products
- Anti-PPP3R1 Immunohistochemistry Kit (VS-0325-XY1727)
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- Species Reactivity: Human, Mouse, Rat
- Target: PPP3R1
- Application: IHC
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For Research Use Only. Not For Clinical Use.
Protein class
Metabolic proteins
Predicted location
Intracellular
Single cell type specificity
Cell type enhanced (Excitatory neurons)
Immune cell specificity
Immune cell enhanced (neutrophil)
Cell line specificity
Low cell line specificity
Interaction
Forms a complex composed of a calmodulin-dependent catalytic subunit (also known as calcineurin A) and a regulatory Ca(2+)-binding subunit (also known as calcineurin B) (PubMed:8524402, 12218175, 12357034, 17498738, 22343722, 23468591, 26794871, 27974827). There are three catalytic subunits, each encoded by a separate gene (PPP3CA, PPP3CB, and PPP3CC) and two regulatory subunits which are also encoded by separate genes (PPP3R1 and PPP3R2). Interacts with catalytic subunit PPP3CA/calcineurin A (PubMed:8524402, 12218175, 12357034, 17498738, 22343722, 23468591, 27974827). Interacts with catalytic subunit PPP3CB/calcineurin A (PubMed:26794871). Interacts with CIB1 (via C-terminal region); the interaction increases upon cardiomyocyte hypertrophy (By similarity). Interacts with RCAN1 (PubMed:12809556). Interacts with SPATA33 (via PQIIIT motif) (PubMed:34446558).
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