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PRDM12
Loading...Anti-PRDM12 Products
- Mouse Anti-PRDM12 Recombinant Antibody (VS3-FY2842) (VS3-FY2842)
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- Species Reactivity: Human, Mouse
- Type: Mouse IgG
- Application: WB
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For Research Use Only. Not For Clinical Use.
Background
This gene encodes a transcriptional regulator of sensory neuronal specification that plays a critical role in pain perception. The encoded protein contains an N-terminal PRDI-BF1 and RIZ homology (PR) domain, a SET domain, and three C-terminal C2H2 zinc finger DNA-binding domains. Naturally occurring mutations in this gene are associated with congenital insensitivity to pain (CIP), and hereditary sensory and autonomic neuropathies (HSAN's) affecting peripheral sensory and autonomic neurons.
