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PREB

Anti-PREB Products

Rabbit Anti-PREB Recombinant Antibody (clone R09-8B7) (VS3-FY1619)
- Species Reactivity: Human, Mouse, Rat
- Type: Rabbit IgG
- Application: WB, IHC-P, IP
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Anti-PREB Immunohistochemistry Kit (VS-0325-XY1738)
- Species Reactivity: Human, Mouse
- Target: PREB
- Application: IHC
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Hi-Affi™ Recombinant Rabbit Anti-PREB Monoclonal Antibody (DS2842AB) (MOR-2842)
- Derivation: Phage display library screening
- Species Reactivity: Human
- Type: IgG
- Application: WB, IHC-P, ICC/IF, IP
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For Research Use Only. Not For Clinical Use.

This gene encodes a protein that specifically binds to a Pit1-binding element of the prolactin (PRL) promoter. This protein may act as a transcriptional regulator and is thought to be involved in some of the developmental abnormalities observed in patients with partial trisomy 2p.

Protein class

Transporters

Predicted location

Intracellular, Membrane (different isoforms)

Single cell type specificity

Cell type enhanced (Plasma cells)

Immune cell specificity

Low immune cell specificity

Cell line specificity

Cell line enhanced (RPMI-8226)

Interaction

Interacts with SAR1B (GDP-bound form) (By similarity). Interacts with MIA2; recruits PREB to endoplasmic reticulum exit sites (PubMed:25202031, 27170179).

Molecular function

Activator, DNA-binding

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