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For Research Use Only. Not For Clinical Use.
Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets
Intracellular
Cell type enhanced (Oligodendrocyte precursor cells, Astrocytes, Inhibitory neurons, Excitatory neurons, Microglial cells)
Not detected in immune cells
Cell line enhanced (ASC diff, fHDF/TERT166)
Interacts (via N-terminus) with ADAP1/CENTA1 (PubMed:12893243). Interacts with MAPK13 (PubMed:19135240). Interacts with DAPK1 in an oxidative stress-regulated manner (PubMed:17703233). Interacts with USP28; the interaction induces phosphorylation of USP28 and activated KRAS-mediated stabilization of ZNF304 (PubMed:24623306). Interacts with AKAP13 (via C-terminal domain) (By similarity).
Kinase, Serine/threonine-protein kinase, Transferase