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PRSS27

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For Research Use Only. Not For Clinical Use.


This gene is located within a large protease gene cluster on chromosome 16. It belongs to the group-1 subfamily of serine proteases. The encoded protein is a secreted tryptic serine protease and is expressed mainly in the pancreas. Alternative splicing results in multiple transcript variants.
Protein class

Enzymes

Predicted location

Secreted

Single cell type specificity

Cell type enhanced (Horizontal cells, Urothelial cells, Squamous epithelial cells, Alveolar cells type 1)

Immune cell specificity

Not detected in immune cells

Cell line specificity

Cell line enhanced (BEWO, SK-BR-3, T-47d, U-266/70)

Molecular function

Hydrolase, Protease, Serine protease

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