PSMC3IP
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Loading...- Mouse Anti-PSMC3IP Recombinant Antibody (PS1026) (VS-0326-YC1026)
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- Species Reactivity: Human
- Type: Mouse IgG1
- Application: IHC
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For Research Use Only. Not For Clinical Use.
Background
This gene encodes a protein that functions in meiotic recombination. It is a subunit of the PSMC3IP/MND1 complex, which interacts with PSMC3/TBP1 to stimulate DMC1- and RAD51-mediated strand exchange during meiosis. The protein encoded by this gene can also co-activate ligand-driven transcription mediated by estrogen, androgen, glucocorticoid, progesterone, and thyroid nuclear receptors. Mutations in this gene cause XX female gonadal dysgenesis.